modelingandcomputationallyintensivemethodsforestimationandprediction¿,held ? atthePolitecnicodiMilano. S. Co. isaforumforthediscussionofnewdevelopments ? September14¿16,2009. Thatof2009isitssixthedition,the?rstonebeingheldinVenice in1999. VI Preface andapplicationsofstatisticalmethodsandcomputationaltechniquesforcomplexand highlydimensionaldatasets. Thebookisaddressedtostatisticiansworkingattheforefrontofthestatistical analysisofcomplexandhighlydimensionaldataandoffersawidevarietyofstatistical models,computerintensivemethodsandapplications. Wewishtothankallassociateeditorsandrefereesfortheirvaluablecontributions thatmadethisvolumepossible. MilanandVenice,May2010 PietroMantovan PiercesareSecchi Contents Space-timetextureanalysisinthermalinfraredimagingforclassi?cation ofRaynaud¿sPhenomenon GrazianoAretusi,LaraFontanella,LuigiIppolitiandArcangeloMerla. . . . . . 1 Mixed-effectsmodellingofKevlar?brefailuretimesthroughBayesian non-parametrics RaffaeleArgiento,AlessandraGuglielmiandAntonioPievatolo. . . . . . . . . . . . 13 Space?llingandlocallyoptimaldesignsforGaussianUniversalKriging AlessandroBaldiAntogniniandMaroussaZagoraiou. . . . . . . . . . . . . . . . . . . . 27 Exploitation,integrationandstatisticalanalysisofthePublicHealth DatabaseandSTEMIArchiveintheLombardiaregion PietroBarbieri,Niccolo`Grieco,FrancescaIeva,AnnaMariaPaganoniand PiercesareSecchi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 Bootstrapalgorithmsforvarianceestimationin PSsampling AlessandroBarbieroandFulviaMecatti. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 FastBayesianfunctionaldataanalysisofbasalbodytemperature JamesM. Ciera. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 AparametricMarkovchaintomodelage-andstate-dependentwear processes MassimilianoGiorgio,MaurizioGuidaandGianpaoloPulcini. . . . . . . . . . . . . 85 CasestudiesinBayesiancomputationusingINLA S