The main objective of this book is the design of Cloud-WSN platforms able to provide a wide range of services to end users and comply with security and QoS requirements. The first contribution consists in designing a self-configurable sensor Cloud-WSN architecture providing QoS-aware and secure healthcare services. The second contribution focus in designing a novel Smartphone Cloud oriented architecture to use smartphones as Observers in order to provide Femtocell attacks detection As A Service to Mobile Network Operators. The third contribution consists in designing a novel Smartphone Cloud architecture able to provide data muling as a service to end users. A game-based model is proposed to optimally reward mobile subscribers for providing data muling services using their smartphones, depending on their trustworthiness and their ability to meet the delivery constraints. In the last contribution, we propose a self-reconfigurable Cloud-based smartphone infrastructure able to provide surveillance-based services to customers. Several interactions are modelled inside the proposed self-reconfigurable Cloud WSN platform using XMPP as an emerging communication protocol.