Desperate Strangers weaves together the lives of five people. Michael Ryan, a gulf war veteran and an attorney in a small Phoenix law firm is asked to represent a former client, Wayne Fuller who is charged with molesting his daughter. In researching his defense, he enlists the aid of a well known criminal attorney, Addam Stein. His paralegal is a beautiful young woman, Jennifer Spencer. She is married to a handsome young Hispanic, Tony Enriquez who is also the client of Addam Stein. Her life changes as she discovers that Tony is a known drug dealer with a sadistic nature. Tony is pressuring Addam to come up with $5 million dollars. He needs to convince Jennifer to seduce Mike into killing Tony. While preparing and trying this case, the web of seduction and murder takes form. The police are called to investigate and the murderer could be any number of suspects. A story of love, seduction and murder come crashing in on all of them.