Tamilselvi, working as a Captain in a leading restaurant, saves the life of a rich customer Ashok, who develops heart attack. She does Cardio Pulmonary Resuscitation (CPR) procedure instantly. Ashok and his wife Priya get to know the life story of Tamilselvi and how she learned CPR.

Tamilselvi, being a brilliant student from a government corporation school in Madurai, couldn't succeed in pursuing medicine degree course due to the new policy of NEET qualifying exam introduced by the union government. Her dreams of becoming a Doctor got shattered, as the NEET was too tough for her, despite scoring very high marks in the State Board Examination. As a mark of gratitude, Ashok helps Tamilselvi realize her dreams. The course of the story portrays the wonderful relationship between Tamilselvi and Ashok's family, and how Tamilselvi shapes her professional career and personal life. Divine Intervention makes a sincere attempt to address a few core issues faced in the contemporary society. The plot conveys a simple message that "the sky is the limit" for youngsters in India to succeed if good opportunities knock at their doors.