Interactions between an anticancer agent and cyclodextrin: Inclusion complex formation and solution thermodynamics - Abhijit Sarkar,Biswajit Sinha
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Cyclodextrins have the ability to solubilize hydrophobic drugs by providing a conical cavity to encapsulate it and hence used for drug delivery. So it is interesting to study the interaction of an anti cancer agent i.e.; gallic acid with cyclodextrin in aqueous media. Different physico-chemical properties such as density, viscosity are used as tools to study the interactions. Uv-spectroscopic study establis ... Full description
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Description
Cyclodextrins have the ability to solubilize hydrophobic drugs by providing a conical cavity to encapsulate it and hence used for drug delivery. So it is interesting to study the interaction of an anti cancer agent i.e.; gallic acid with cyclodextrin in aqueous media. Different physico-chemical properties such as density, viscosity are used as tools to study the interactions. Uv-spectroscopic study establishes formaion of 1:1 inclusion complex. Various results reveal that the solutions are characterized predominantly by solute -solvent interactions and gallic acid behaves as a long-range structure maker.
More Information
| Author | Abhijit Sarkar, Biswajit Sinha |
|---|---|
| Publisher | LAP LAMBERT Academic Publishing |
| Release year | 2017 |
| Cover type | Softcover |
| EAN | 9783330044425 |