Killer Lymphocytes - Gideon Berke,William R. Clark
-20% with code BOOKS
Shipping in 12-18 days
30-day return policy
The existence of a unique kind of immune cell ¿ the killer lymphocyt- which destroys other cells in a highly specific manner, has fascinated immunologists for almost half a century. How do these cells, whose precursors have lived in communal harmony with their host, decide that some of their cohabitants must die? And how do they kill them? The definition of killer lymphocytes came from discovery of their ro ... Full description
You May Also Like
TOP
The Myth of Normal: Trauma, Illness, and Healing in a Toxic Culture
-20% with code BOOKS
In stock at our supplier
TOP
The Checklist Manifesto: How to Get Things Right
-20% with code BOOKS
In stock at our supplier
TOP
No Bad Parts: Healing Trauma and Restoring Wholeness with the Internal Family Systems Model
-20% with code BOOKS
In stock at our supplier
TOP
On Connection: 'Powerful' MATT HAIG
-20% with code BOOKS
In stock at our supplier
TOP
Harrison's Principles of Internal Medicine (Vol.1 & Vol.2)
Stephen Hauser, Joseph Loscalzo, Steven Holland, Dan Longo, J. Larry Jameson, Dennis Kasper, Carol Langford, Anthony Fauci
-20% with code BOOKS
In stock at our supplier
TOP
The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma
-20% with code BOOKS
In stock at our supplier
TOP
Oxford Handbook of Anaesthesia
-20% with code BOOKS
In stock at our supplier
TOP
Maybe You Should Talk to Someone: a therapist, her thearapist, and our lives revealed
-20% with code BOOKS
In stock at our supplier
TOP
How Not To Die: Discover the foods scientifically proven to prevent and reverse disease
-20% with code BOOKS
In stock at our supplier
TOP
Lifespan: Why We Age - and Why We Don't Have To
-20% with code BOOKS
In stock at our supplier
TOP
Vademecum Metabolicum: Diagnosis and Treatment of Inborn Errors of Metabolism Forword by William L. Nyhan, San Diego, USA
Johannes Zschocke, Georg F. Hoffmann
-20% with code BOOKS
In stock at our supplier
TOP
Cellular and Molecular Immunology
Sarah Henrickson, Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai
-20% with code BOOKS
In stock at our supplier
TOP
Physics, Pharmacology and Physiology for Anaesthetists: Key Concepts for the FRCA
Matthew E. Cross, Emma V. E. Plunkett
-20% with code BOOKS
In stock at our supplier
TOP
Pocket Guide to Teaching for Clinical Instructors
-20% with code BOOKS
In stock at our supplier
TOP
Oxford Handbook of Critical Care
Andrew Webb, Mervyn Singer, Alice Carter
-20% with code BOOKS
In stock at our supplier
TOP
The Wills Eye Manual: Print + eBook with Multimedia: Office and Emergency Room Diagnosis and Treatment of Eye Disease
-20% with code BOOKS
In stock at our supplier
TOP
Who Deserves Your Love: How to Create Boundaries to Start, Strengthen or End Any Relationship
-20% with code BOOKS
In stock at our supplier
TOP
Vaccinated - dead: Histopathological findings following COVID-19 vaccination
-20% with code BOOKS
In stock at our supplier
TOP
Steal Like an Artist: 10 Things Nobody Told You About Being Creative
-20% with code BOOKS
In stock at our supplier
TOP
It Didn't Start with You: How Inherited Family Trauma Shapes Who We Are and How to End the Cycle
-20% with code BOOKS
In stock at our supplier
Description
The existence of a unique kind of immune cell ¿ the killer lymphocyt- which destroys other cells in a highly specific manner, has fascinated immunologists for almost half a century. How do these cells, whose precursors have lived in communal harmony with their host, decide that some of their cohabitants must die? And how do they kill them? The definition of killer lymphocytes came from discovery of their roles in a wide range of in vivo phenomena such as transplant rejection, virus infection and its related immunopathologies, and anti-tumor responses. Yet for the most part almost everything we know about these cells has come from studying them in vitro. They have yielded their secrets slowly and reluctantly. To understand fully how they work, geneticists and immunologists had to unravel the major histocompatibility systems of vertebrates, a long and torturous road that provided some of the darkest hours of immunology. The search for antigen-sensing receptors on both T cells and NK cells was scarcely less frustrating. And the holy grail of ce- mediated cytotoxicity ¿ defining the mechanism by which killer cells take down their adversaries ¿ sorely tested the ingenuity, patience and mutual good will of laboratories around the world. These questions have now largely been answered. But do we really understand these cells? We can tame them to a large degree in transplant rejection. It may yet turn out that we can harness their immunotherapeutic potential in treating viral and malignant disease.
More Information
| Author | Gideon Berke, William R. Clark |
|---|---|
| Publisher | Springer Netherlands |
| Release year | 2007 |
| Cover type | Softcover |
| EAN | 9781402065637 |