Man-Machine Interaction is an interdisciplinary field of research that covers many aspects of science focused on a human and machine in conjunction. Basic goal of the study is to improve and invent new ways of communication between users and computers, and many different subjects are involved to reach the long-term research objective of an intuitive, natural and multimodal way of interaction with machines. The rapid evolution of the methods by which humans interact with computers is observed nowadays and new approaches allow using computing technologies to support people on the daily basis, making computers more usable and receptive to the user's needs. This monograph is the third edition in the series and presents important ideas, current trends and innovations in the man-machine interactions area. The aim of this book is to introduce not only hardware and software interfacing concepts, but also to give insights into the related theoretical background. Reader is provided with a compilation of high-quality original papers covering a wide scope of research topics divided into eleven sections, namely: human-computer interactions, robot control, embedded and navigation systems, bio data analysis and mining, biomedical signal processing, image and sound processing, decision support and expert systems, rough and fuzzy systems, pattern recognition, algorithms and optimization, computer networks and mobile technologies and data management systems.