Microarray Technology in Practice - Steve Russell,Lisa A. Meadows,Roslin R. Russell
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Using chips composed of thousands of spots, each with the capability of holding DNA molecules corresponding to a given gene, DNA microarray technology has enabled researchers to measure simultaneously gene expression across the genome. As with other large-scale genomics approaches, microarray technologies are broadly applicable across disciplines of life and biomedical sciences, but remain daunting to many ... Full description
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Description
- Cohesive overview of the technology and available platforms, followed by detailed discussion of experimental design and analysis of microarray experiments
- Up-to-date description of normalization methods and current methods for sample amplification and labeling
- Deep focus on oligonucleotide design, printing, labeling and hybridization, data acquisition, normalization, and meta-analysis
- Additional uses of microarray technology such as ChIP (chromatin immunoprecipitation) with hybridization to DNA arrays, microarray-based comparative genomic hybridization (CGH), and cell and tissue arrays
More Information
| Author | Steve Russell, Lisa A. Meadows, Roslin R. Russell |
|---|---|
| Publisher | Elsevier Science |
| Release year | 2008 |
| Cover type | Softcover |
| EAN | 9780123725165 |