The Pathologist describes the life of David Weber, who follows in his father's footsteps by working as a pathologist, and his closest friends, his colleagues of the hospital's Pathology Department. The group have a joint liking for drugs and women but tormented by a tragic past, David becomes increasingly out of control with combinations of drugs and alcohol.

David's past has a huge part to play in how he reacts to situations and he sometimes makes decisions that he regrets. No stranger to death, David understands very well, that fighting for life can be hard, but increasing despair forces him to question whether the battle is really worth it. Thank goodness for his small circle of friends, who look after him at every given turn, making the most impossible decisions for him.