A thorough and timely update, this new edition presents principles, techniques, and applications in this sub-discipline of analytical chemistry for quantifying traces of potentially toxic organic and inorganic chemical substances found in air, soil, fish, and water, as well as serum, plasma, urine, and other body fluids. The author addresses regulatory aspects, calibration, verification, and the statistical treatment of analytical data including instrument detection limits; quality assurance/quality control; sampling and sample preparation; and techniques that are used to quantify trace concentrations of organic and inorganic chemical substances.Key Features:Fundamental principles are introduced for the more significant experimental approaches to sample preparationPrinciples of instrumental analysis (determinative techniques) for trace organics and trace inorganics analysisAn introduction to the statistical treatment of trace analytical dataHow to calculate instrument detection limits based on weighted least squares confidence band calibration statisticsIncludes an updated series of student-tested experiments